Have you heard of FPIES?

Unfortunately it’s not a culinary delight, but rather a once rare disorder with its roots in allergy and immunology. FPIES, Food Protein Induced Enterocolitios Syndrome, presents generally in the first year of life with a delayed but violent vomiting response to a typically non-allergenic food; namely sweet potatoes, chicken and rice to name a few – foods typically introduced first to infants. Dairy and soy can also be FPIES offenders, but in the case of this type of allergic response, hives and wheezing are not present. Even more interesting, the onset of vomiting is typically several hours after ingestion, rather than within minutes. A typical allergic response is noted to be IgE (immunoglobulin) mediated – or resulting from an overwhelming number of antibodies primed against a specific food protein. FPIES is not mediated by antibodies but rather immune system protector cells, and thus cannot be screened for by skin prick testing or serum testing…